To solve C:\windows\system32\config\systemprofile\desktop refers to a location that is unavailable you must reset the path that your computer defaults to on startup. If it still cannot be located, the information might have been moved to a different location.' Check to make sure that the disk is properly inserted, or that you are connected to the Internet or your network, and then try again. It could be on a hard drive on this computer, or on a network. 'C:\Windows\system32\config\systemprofile\Desktop refers to a location that is unavailable. The system crash can occasionally occur while the computer is shutting down or during a Windows update, so you will be completely baffled when you first encounter this error. If this happens, your system files have been damaged or corrupted in some way. Your application and folder icons will be nowhere to be found and you’ll be hit with an error that begins with “C:\windows\system32\config\systemprofile\desktop refers to a location that is unavailable”.
Sometimes when your PC's system crashes, you’ll log into an empty desktop when you start your computer. Press the 'Windows + R' keys simultaneously to pull up 'Run', type regedit and press enter. Go to C drive, click the 'Users folder' and then your username. Go to the C drive, click the 'Users' folder and then your username.
